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[DOI] [PMC free article] [PubMed] [Google Scholar] Wu G., Knabe D.A

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Upon delivery of B12 to the tissues by holo TC, receptor-mediated endo­cytosis occurs, after which holoTC enters acidic lysosomes where the trans­cobalamin protein is degraded, the B12 is released, and then converted to its cofactor forms (Allen et al., 2018)