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Cysteine is subsequently used for glutathione (GSH) biosynthesis (and other biomolecules) and is involved in antioxidant defense mechanism, it is considered to be the rate-limiting precursor of the antioxidant glutathione [36]

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Correspondingly, the inhibition of NF-κB by BAY 11-7082 significantly increased the survived SGN numbers, while decreased the C-CASP3 positive SGN numbers and the C-CASP3 expression in peroxynitrite + BAY 11-7082 group compared with the peroxynitrite group (Figures 9D–F)

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