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415 Given the adaptability of CSCs, combination therapies incorporating metabolic inhibitors, immune activation, and CSC-specific targeting agents are being explored as potential strategies to improve treatment efficacy and prevent tumor relapse

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In light of these findings, the elevated prefrontal GSH levels observed in participants with current but not remitted depression may reflect a compensatory upregulation in GSH levels, possibly in response to an increase in perceived stress, although no association between GSH and cortisol levels was observed