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It is characterized by social communication impairments, repetitive and stereotyped behaviors, restricted interests, and sensory perception abnormalities ( 2 GABA plays a crucial role in the process of neurodevelopment The dysfunction of the brain’s excitatory-inhibitory circuitry or the imbalance of excitatory and inhibitory neurotransmitters within this circuitry underlies many neuropsychiatric abnormalities

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– Downstream observations in models include transcriptional changes consistent with enhanced mitochondrial function and lipid utilization