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Also pretreatment with glutathione significantly decreased sensitivity of mPTP to calcium (Figure 2B) which could indicate increased or restored Ca 2+ capacity of mitochondria of old rat heart

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Tafazoli and O’Brien, 2009) and in vivo (Shimizu et al., 2009), the exact cellular mechanisms and pathways of AQ-QI and DEAQ-QI toxicity remain poorly understood